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Lactobacilli are bacteria that normally live in the human small intestine and vagina. Human studies report mixed results in the improvement of irritable bowel syndrome (IBS) symptoms after taking Lactobacillus acidophilus by mouth.
One human study using L. acidophilus in combination with another bacterium (B. infantis) in infants reported fewer cases of necrotizing enterocolitis (severe inflammation of the gut) and no complications related to treatment. Additional research is necessary in this area before a conclusion can be drawn.
Lactobacillus acidophilus may be difficult to tolerate if allergic or hypersensitive to dairy products. Avoid with a history of an injury or illness of the intestinal wall, immune-disease, or heart valve surgery. Avoid if taking prescription drugs, such as corticosteroids, because there is a risk of infection. Use cautiously with heart murmurs. Antibiotics or alcohol may destroy Lactobacillus acidophilus. Therefore, it is recommended that Lactobacillus acidophilus be taken three hours after taking antibiotics or drinking alcohol. Some individuals can use antacids, such as famotidine (Pepcid) or esomeprazole (Nexium), to decrease the amount of acid in the stomach one hour before taking Lactobacillus acidophilus.
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