|
- General: Patients should be continually followed by their physician to be assessed for declining physical and mental functioning. Depending on the type of mucopolysaccharidosis (MPS), patients may need to be evaluated more often than others due to differences in disease progression and severity.
- Cardiovascular: Common heart abnormalities may include valve defects, thickening and stiffening of the heart wall, and narrowing of blood vessels. Complications of heart abnormalities are cardiovascular collapse and death if not corrected. Surgery and prescription medications may be useful in preventing complications.
- Respiratory: Effects on breathing function include sleep apnea, obstructive airway disease, chronic respiratory infection, enlarged tonsils and adenoids, and noisy and difficult breathing. Chronic respiratory infections can lead to pneumonia, which can be life-threatening if untreated. Enlarged adenoids and tonsils may contribute to difficulty breathing and sleep apnea.
- Skeletal: Abnormal bone size and shape and joint pain and stiffness may lead to decreased mobility and quality of life. Bone abnormalities may compress nerves and press on organs, leading to inhibition of normal neurological function, organ function, and even paralysis.
 |
Learn
