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Some causes for male infertility may include: Retrograde ejaculation: This condition occurs when the bladder does not close during ejaculation because of impaired bladder muscles or nerves. Klinefelter syndrome: This is a congenital condition in which there is an extra X-chromosome present leading to male infertility. Hormonal disorder: Certain hormone deficiencies cause deficiencies in testosterone (the male sex hormone) that lead to infertility. Acquired causes:
Radiation and chemotherapy
Certain infections such as meningitis and syphilis
Disruption or damage to testicles, hypothalamus, and pituitary glands
Malformation of the glands
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