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- Medications: Some medications that may cause acne include anabolic steroids (sometimes used illegally by athletes to "bulk up"), some anti-seizure medications, the anti-tuberculosis drugs isoniazid and rifampin, lithium and iodine-containing medications.
- Chronic physical pressure on the skin: Chafing from the straps of a backpack or tucking a violin between the jaw and chin can cause chronic physical pressure on the skin and may induce a condition known as acne mechanica.
- Chlorinated industrial chemicals: These may induce the occupational skin disorder known as chloracne.
- Metabolic conditions: Changes in the hormonal balance, such as those brought about by pregnancy, menstruation or hormonal abnormalities may induce acne.
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